Adult Olfactory Bulb Neurogenesis
نویسندگان
چکیده
منابع مشابه
Adult Subventricular Zone and Olfactory Bulb Neurogenesis
IN THE ADULT MAMMALIAN BRAIN, NEW NEURONS are added to the olfactory bulb (OB) throughout life. In rodents, the adult germinal region for OB neurogenesis is the subventricular zone (SVZ), a layer of cells found along the walls of the brain lateral ventricles (for review, see Alvarez-Buylla and Garcia-Verdugo 2002). Neuroblasts born in the SVZ migrate a relatively long distance into the OB where...
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Subventricular zone (SVZ) neurogenesis continuously provides new GABA- and dopamine (DA)-containing interneurons for the olfactory bulb (OB) in most adult mammals. DAergic interneurons are located in the glomerular layer (GL) where they participate in the processing of sensory inputs. To examine whether adult neurogenesis might contribute to regeneration after circuit injury in mice, we induce ...
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Most mammalian brain cells develop from neural progenitor or stem cells that reside in the ventricular and subventricular zone. Interestingly, in rodents and primates, neurogenesis does not end when the olfactory bulb reaches adult size but rather continues throughout life (Kaplan et al., 1985; Kuhn et al., 1996; Pencea et al., 2001). For neurons at two locations in the olfactory bulb, the gran...
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Neurogenesis, the division, migration, and differentiation of new neurons, occurs throughout life. Brain derived neurotrophic factor (BDNF) has been identified as a potential signaling molecule regulating neurogenesis in the subventricular zone (SVZ), but its functional consequences in vivo have not been well defined. We report marked and unexpected deficits in survival but not proliferation of...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Perspectives in Biology
سال: 2016
ISSN: 1943-0264
DOI: 10.1101/cshperspect.a018945